In cases where you have to send large files, you can always use the usual compression software such as Winzip or Winrar to save on space. The larger files sent as is will take a long time to download and worst, some may even linger in the mail server causing unnecessary space that may eventually lead for other incoming mails to bounce.
While some people would not be religious in checking their emails daily, these are factors that contribute towards clogging up your email box. The best way to go is to try and decrease the size of the file. Compressing them is just one of it.